Reduce the participant burden putting clinical trials at risk.

Clinical trial protocols are becoming more complex, placing greater demands on participants and increasing the risk of missed visits, poor adherence, dropout and delays to trial delivery.

Trial Flow translates complex protocols into clear, study-specific support that improves participant readiness, strengthens retention and helps keep studies on track.

Trial Flow app home screen supporting patients of all ages and their caregivers

How Trial Flow works

Every study is different. Trial Flow is configured to match.

Trial Flow translates complex study protocols into clear, study-specific participant support, configured to the unique requirements of every trial. 

  • Educational: Clear, study-specific information that explains what's expected throughout the trial.

  • Logistical: Practical guidance, reminders and visit preparation that reduce avoidable participant burden.

  • Emotional: Tools that build confidence and help participants cope with difficult or demanding moments in the study.

  • Motivational: Progress tracking and encouragement that help participants stay engaged.

 

Diagram showing the patient benefit of different Trial Flow features

Participant burden puts trial delivery at risk.

As clinical trial protocols become more demanding, participants face more procedures, more visits and more information to manage. Every additional demand increases the risk of missed visits, poor adherence and participant dropout.

Trial Flow closes that gap with protocol-aligned participant support that improves participant readiness, reduces avoidable participant burden and helps keep studies on track.

6x
more data points

60%
more procedures

50%
more research sites

Average phase III clinical trial (2015 - 2025)

Supporting every participant. Strengthening trial delivery.

Family interacting with a Trial Flow study app

Participants & caregivers

Support tailored to children, adolescents, adults and caregivers, with study-specific guidance throughout every stage.

Research site staff reviewing trial information on a clipboard

Research sites

Better prepared participants mean fewer repetitive questions, reduced site burden and more reliable study delivery.

Trial team reviewing their retention strategy

Sponsors & CROs

Improved participant readiness supports adherence, strengthens retention and keeps studies on track.

Download the Little Journey app

A free smartphone app designed for patients and families

Our app is loved by families and healthcare staff alike. Don’t just take our word for it, download it today!

Rated 4.7 stars on the App Store

Download Little Journey on the App Store
Download Little Journey on Google Play
A parent and their child are sat together, both interacting with a tablet.

Built on evidence. Designed for participation.

Built on more than a decade of experience, Trial Flow combines behavioural science with real-world insight to design participant support that improves readiness throughout the study.

Logistical

Co-designed with participants

We work alongside participants, caregivers, clinical teams and researchers to understand real-world needs and design support that fits around everyday life.

Grounded in behavioural science

Every journey is designed to address the practical, emotional and educational needs of participants throughout the study.

Proven in practice

Built by the team behind Little Journey, Trial Flow brings more than a decade of experience designing and delivering digital support across healthcare and clinical research.

50,000+

Participants supported

 Across healthcare and clinical research.

95%

Average
site uptake

Designed for existing site workflows.

Up to 53%

Fewer
dropouts

Better participant engagement.

12-16

Weeks
deployment

Protocol-aligned and study-specific.

Ready to reduce participant burden in your next trial?

See how Trial Flow is configured to your study protocol and delivers tailored participant support throughout every stage of the trial.

Trial Flow demo screens