Insights & Resources
Explore learnings from our research and practical resources to help your team to better understand patient support, assess burden across trials, and build strategies that improve adherence and retention.

Guide
Retention solution RFP Guide: Procuring for participant retention in clinical trials
Avoidable attrition can reduce the completeness and credibility of trial findings and create opportunity costs from resources already invested in recruitment and follow-up.
The aim of this guide is to give study teams a practical set of prompts that can help them write clear RFP briefs, compare vendor responses more consistently, and select support that is designed around the needs of the people taking part.
Checklist
Procuring for participant retention: Can your retention partner answer these 7 questions?
Different studies create different demands for participants, caregivers, sites and sponsors. These discussion prompts are designed to help teams look beyond individual features and understand how a proposed solution fits the protocol, responds to participant needs, can be implemented in practice and will be measured. Use them in early conversations, partner evaluation or preparation for a more detailed procurement process.
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White paper
A Retention ROI Model for clinical trials: improving patient engagement, adherence, retention and trial efficiency
This white paper introduces Trial Flow’s Retention ROI Model, grounded in a Theory of Change approach. It explores how protocol aligned participant support may reduce burden, improve understanding and strengthen motivation, while helping sponsors identify how its contribution to participant and study outcomes can be measured.
Checklist
Digital patient support scalability checklist
This checklist helps sponsors and CROs assess whether their current digital patient support model is truly scalable across studies, sites and patient populations. It highlights common gaps around value and visibility, study-to-study reuse, structured journey support, operational readiness and governance. Designed to help teams identify where fragmented delivery, hidden manual effort or limited reporting may be holding back efficient trial delivery.


Whitepaper
Voices Unheard: Parents of Autistic Children in Paediatric Care
This white paper explores the often-overlooked experiences of parents navigating healthcare systems with their autistic children. Authored by clinical psychologists Dr. Megan Hofmann and Dr. Vicky Queralt, the paper concludes with actionable recommendations tailored for healthcare settings, staff, and families — all aimed at fostering more compassionate, effective, and inclusive care.
Whitepaper
The Benefits of Play in Healthcare Environments
In this whitepaper, we focus on the long-established benefits of play within healthcare settings, highlighting how providing children with information about their healthcare journey in playful ways, along with them sharing their strengths and needs, that healthcare experiences will be significantly improved for all.

Latest Trial Flow Insights
Explore articles on patient support, trial retention, co-design, behavioural science and scalable delivery across clinical trials.

Rethinking retention: from individual interventions to participation support

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